The drug of choice is cisplatin, a well-known anticancer drug, used in the treatment of various cancer types.
The chitosan polymer was selected in this study because of the high poly-cationic, biodegradable and biocompatible characters. As a step-in formulation studies the work has been limited to studying the various physical characters of CCNP using a zeta nanosizer. The ultimate aim of this research work is to develop a cisplatin loaded chitosan nanoparticle system (CCNP) to facilitate the release of cisplatin in a more sustained manner to improve therapeutic efficacy via the reduction of its toxicity. PREPARATION AND PHYSICAL CHARACTERIZATION OF CISPLATIN CHITOSAN NANOPARTICLES BY ZETA NANOSIZER “PRIME STEP FOR FORMULATION AND DEVELOPMENT” Abstract
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